Light therapy is certainly having a moment. There are now available glowing gadgets for everything from skin conditions and wrinkles to sore muscles and gum disease, the newest innovation is a dental hygiene device enhanced with small red light diodes, described by its makers as “a significant discovery for domestic dental hygiene.” Internationally, the sector valued at $1bn last year is expected to increase to $1.8bn within the next decade. There are even infrared saunas available, where instead of hot coals (real or electric) heating the air, your body is warmed directly by infrared light. According to its devotees, the experience resembles using an LED facial mask, boosting skin collagen, soothing sore muscles, reducing swelling and chronic health conditions while protecting against dementia.
“It appears somewhat mystical,” says a Durham University professor, professor in neuroscience at Durham University and a convert to the value of light therapy. Naturally, we know light influences biological functions. Sunlight enables vitamin D production, essential for skeletal strength, immune function, and muscular health. Light exposure controls our sleep-wake cycles, additionally, activating brain chemicals and hormonal responses in daylight, and winding down bodily functions for sleep as it fades into night. Sunlight-imitating lamps are a common remedy for people with seasonal affective disorder (Sad) to boost low mood in winter. Clearly, light energy is essential for optimal functioning.
Although mood lamps generally utilize blue-spectrum frequencies, the majority of phototherapy tools use red or near-infrared wavelengths. In rigorous scientific studies, like examinations of infrared influence on cerebral tissue, determining the precise frequency is essential. Light is a form of electromagnetic radiation, which runs the spectrum from the lowest-energy, longest wavelengths (radio waves) to the highest-energy (gamma waves). Therapeutic light application utilizes intermediate light frequencies, with ultraviolet representing the higher energy invisible light, followed by visible light encompassing rainbow colors and infrared light visible through night vision technology.
Ultraviolet treatment has been employed by skin specialists for decades to treat chronic skin conditions such as eczema, psoriasis and vitiligo. It modulates intracellular immune mechanisms, “and suppresses swelling,” notes Dr Bernard Ho. “There’s lots of evidence for phototherapy.” UVA reaches deeper skin layers compared to UVB, while the LEDs in consumer devices (which generally deliver red, infrared or blue light) “tend to be a bit more superficial.”
Potential UVB consequences, including sunburn or skin darkening, are recognized but medical equipment uses controlled narrow-band delivery – signifying focused frequency bands – that reduces potential hazards. “It’s supervised by a healthcare professional, so the dosage is monitored,” says Ho. Most importantly, the devices are tuned by qualified personnel, “to guarantee appropriate wavelength emission – as opposed to commercial tanning facilities, where it’s a bit unregulated, and emission spectra aren’t confirmed.”
Colored light diodes, he says, “aren’t really used in the medical sense, but could assist with specific concerns.” Red wavelength therapy, proponents claim, improve circulatory function, oxygen utilization and cell renewal in the skin, and promote collagen synthesis – an important goal for anti-aging. “Research exists,” states the dermatologist. “However, it’s limited.” Regardless, amid the sea of devices now available, “it’s unclear if device outputs match study parameters. Appropriate exposure periods aren’t established, ideal distance from skin surface, if benefits outweigh potential risks. Numerous concerns persist.”
Initial blue-light devices addressed acne bacteria, a microbe associated with acne. Research support isn’t sufficient for standard medical recommendation – although, notes the dermatologist, “it’s frequently employed in beauty centers.” Certain patients incorporate it into their regimen, he mentions, however for consumer products, “we just tell them to try it carefully and to make sure it has been assessed for safety. Unless it’s a medical device, the regulation is a bit grey.”
Meanwhile, in advanced research areas, researchers have been testing neural cells, discovering multiple mechanisms for infrared’s cellular benefits. “Pretty much everything I did with the light at that particular wavelength was positive and protective,” he reports. It is partly these many and varied positive effects on cellular health that have driven skepticism about light therapy – that claims seem exaggerated. However, scientific investigation has altered his perspective.
Chazot mostly works on developing drug treatments for neurodegenerative diseases, however two decades past, a doctor developing photonic antiviral treatment consulted his scientific background. “He developed equipment for cellular and insect experiments,” he says. “I was pretty sceptical. The specific wavelength measured approximately 1070nm, that nobody believed did anything biological.”
What it did have going for it, however, was its efficient water penetration, enabling deeper tissue penetration.
Growing data suggested infrared influenced energy-producing organelles. Mitochondria produce ATP for cell function, producing fuel for biological processes. “All human cells contain mitochondria, including the brain,” says Chazot, who concentrated on cerebral applications. “Research confirms improved brain blood flow with phototherapy, which is generally advantageous.”
With specific frequency application, energy organelles generate minimal reactive oxygen compounds. In limited quantities these molecules, notes the scientist, “stimulates so-called chaperone proteins which look after your mitochondria, protect cellular integrity and manage defective proteins.”
These processes show potential for neurological conditions: free radical neutralization, anti-inflammatory, and waste removal – autophagy representing cellular waste disposal.
Upon examining current studies on light therapy for dementia, he says, several hundred individuals participated in various investigations, including his own initial clinical trials in the US
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